COVID-19 Vaccine Clinical Trials-Study-Pfizer-90% efficiency

Courtesy-Pfizer
  • Out of the 2 vaccine candidates used, one has been proved effective at 90%
  • 90% is achieved at 7 days after the second dose, implying patients are likely to become covid immune after 28 days
  • About 43,000 people have participated in this clinical trial, out of these, 38,000 people have been given the second dose
  • 30% of participants in this study are from different racial and ethnic backgrounds
  • It is an RNA based vaccine
  • This vaccine encoding a viral antigen, which is then expressed by the vaccine recipient as a protein capable of eliciting protective immune responses
  • These are not a live-attenuated vaccine approach, which has the possibility of live infection and take more time for vaccine development
  • 1 or 2 doses is prepared, in general, any new vaccine starts with more dosage to improve the efficacy
  • 7 days, 1 month, and 6 months after-effects is validated after the vaccine injection
  • Healthy adults, participants without evidence of infection, confirmed COVID-19, confirmed severe patients are included in these trials
  • It is a multicenter, multinational, randomized, placebo-controlled study, implying it is fool-proof and includes a diversity of patients
  • Age groups of 18–55, 65–85, and ≥ 16 years of age has been covered in these trials
  • Like all clinical trials, the majority of them will receive the injection, and the minority participants receiving the placebo
  • Participants are furnished, low-medium, and high dosage, consent is sought, blood samples, all body vitals pre-screened, and checked regularly in periods of time2
  • Placebo is a saline injection, and others administered the actual two vaccine candidates
  • Like all trials, there would be blinded clinical staff to perform this study in a risk-free fashion
  • All systemic events like headache, fever, diarrhea, vomiting, are validated and sampled
  • Detailed roadmaps of vaccine test days, monitoring days, with every event planned in detail for this study has been carried out by Pfizer
  • The study is stopped in the event of more patients exhibiting severe symptoms

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